Salinomycin Activates AMP-Activated Protein Kinase-Dependent Autophagy in Cultured Osteoblastoma Cells: A Negative Regulator against Cell Apoptosis

BACKGROUND: The malignant osteoblastoma has poor prognosis, thus the search for novel and more efficient chemo-agents against this disease is urgent. Salinomycin induces broad anti-cancer effects both in vivo and in vitro, however, its role in osteoblastoma is still not clear. KEY FINDINGS: Salinomy...

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Detalles Bibliográficos
Autores principales: Zhu, Lun-qing, Zhen, Yun-fang, Zhang, Ya, Guo, Zhi-xiong, Dai, Jin, Wang, Xiao-dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866127/
https://www.ncbi.nlm.nih.gov/pubmed/24358342
http://dx.doi.org/10.1371/journal.pone.0084175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866127/
https://www.ncbi.nlm.nih.gov/pubmed/24358342
http://dx.doi.org/10.1371/journal.pone.0084175

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