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Highly Efficient Generation of GGTA1 Biallelic Knockout Inbred Mini-Pigs with TALENs
Inbred mini-pigs are ideal organ donors for future human xenotransplantations because of their clear genetic background, high homozygosity, and high inbreeding endurance. In this study, we chose fibroblast cells from a highly inbred pig line called Banna mini-pig inbred line (BMI) as donor nuclei fo...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866186/ https://www.ncbi.nlm.nih.gov/pubmed/24358349 http://dx.doi.org/10.1371/journal.pone.0084250 |