Cargando…

Argonaute-3 activates the let-7a passenger strand microRNA

MicroRNA duplices are separated into a guide and a passenger strand. By convention, the guide represents the active microRNA while the passenger is supposedly degraded. However, passenger strands also emerge as active microRNAs. It is unknown whether the guide-to-passenger-strand ratio can be active...

Descripción completa

Detalles Bibliográficos
Autores principales: Winter, Julia, Diederichs, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866245/
https://www.ncbi.nlm.nih.gov/pubmed/24100239
http://dx.doi.org/10.4161/rna.26424