Gene Expression Profiling of Early Hepatic Stellate Cell Activation Reveals a Role for Igfbp3 in Cell Migration

BACKGROUND: Scarring of the liver is the result of prolonged exposure to exogenous or endogenous stimuli. At the onset of fibrosis, quiescent hepatic stellate cells (HSCs) activate and transdifferentiate into matrix producing, myofibroblast-like cells. AIM AND METHODS: To identify key players during...

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Detalles Bibliográficos
Autores principales: Mannaerts, Inge, Schroyen, Ben, Verhulst, Stefaan, Van Lommel, Leentje, Schuit, Frans, Nyssen, Marc, van Grunsven, Leo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866247/
https://www.ncbi.nlm.nih.gov/pubmed/24358328
http://dx.doi.org/10.1371/journal.pone.0084071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866247/
https://www.ncbi.nlm.nih.gov/pubmed/24358328
http://dx.doi.org/10.1371/journal.pone.0084071

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