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A Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR (-/-) Mice

BACKGROUND: Nonalcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty liver disease and a risk factor for cirrhosis, hepatocellular carcinoma and liver failure. Previously, we reported that dietary docosahexaenoic acid (DHA, 22:6,n-3) was more effective than eicosapentaenoic ac...

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Detalles Bibliográficos
Autores principales: Depner, Christopher M., Traber, Maret G., Bobe, Gerd, Kensicki, Elizabeth, Bohren, Kurt M., Milne, Ginger, Jump, Donald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866250/
https://www.ncbi.nlm.nih.gov/pubmed/24358308
http://dx.doi.org/10.1371/journal.pone.0083756