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A 3D multiscale model of cancer stem cell in tumor development

BACKGROUND: Recent reports indicate that a subgroup of tumor cells named cancer stem cells (CSCs) or tumor initiating cells (TICs) are responsible for tumor initiation, growth and drug resistance. This subgroup of tumor cells has self-renewal capacity and could differentiate into heterogeneous tumor...

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Detalles Bibliográficos
Autores principales: Li, Fuhai, Tan, Hua, Singh, Jaykrishna, Yang, Jian, Xia, Xiaofeng, Bao, Jiguang, Ma, Jinwen, Zhan, Ming, Wong, Stephen TC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866259/
https://www.ncbi.nlm.nih.gov/pubmed/24564919
http://dx.doi.org/10.1186/1752-0509-7-S2-S12