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Intravenous palonosetron increases the incidence of QTc prolongation during sevoflurane general anesthesia for laparotomy

BACKGROUND: Palonosetron is a recently introduced 5-hydroxytryptamine-3 (5-HT(3)) receptor antagonist useful for postoperative nausea and vomiting prophylaxis. However, 5-HT(3) receptor antagonists increase the corrected QT (QTc) interval in patients who undergo general anesthesia. This retrospectiv...

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Detalles Bibliográficos
Autores principales: Min, Jeong Jin, Yoo, Yongjae, Kim, Tae Kyong, Lee, Jung-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Anesthesiologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866334/
https://www.ncbi.nlm.nih.gov/pubmed/24363841
http://dx.doi.org/10.4097/kjae.2013.65.5.397