EXPANDS: expanding ploidy and allele frequency on nested subpopulations

Motivation: Several cancer types consist of multiple genetically and phenotypically distinct subpopulations. The underlying mechanism for this intra-tumoral heterogeneity can be explained by the clonal evolution model, whereby growth advantageous mutations cause the expansion of cancer cell subclone...

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Detalles Bibliográficos
Autores principales: Andor, Noemi, Harness, Julie V., Müller, Sabine, Mewes, Hans W., Petritsch, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866558/
https://www.ncbi.nlm.nih.gov/pubmed/24177718
http://dx.doi.org/10.1093/bioinformatics/btt622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866558/
https://www.ncbi.nlm.nih.gov/pubmed/24177718
http://dx.doi.org/10.1093/bioinformatics/btt622

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