Id4 dependent acetylation restores mutant-p53 transcriptional activity

BACKGROUND: The mechanisms that can restore biological activity of mutant p53 are an area of high interest given that mutant p53 expression is observed in one third of prostate cancer. Here we demonstrate that Id4, an HLH transcriptional regulator and a tumor suppressor, can restore the mutant p53 t...

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Detalles Bibliográficos
Autores principales: Knowell, Ashley E, Patel, Divya, Morton, Derrick J, Sharma, Pankaj, Glymph, Shanora, Chaudhary, Jaideep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866570/
https://www.ncbi.nlm.nih.gov/pubmed/24330748
http://dx.doi.org/10.1186/1476-4598-12-161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866570/
https://www.ncbi.nlm.nih.gov/pubmed/24330748
http://dx.doi.org/10.1186/1476-4598-12-161

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