The N-terminal region of influenza virus polymerase PB1 adjacent to the PA binding site is involved in replication but not transcription of the viral genome

The influenza virus genome forms viral ribonucleoprotein (vRNP) complexes with nucleoprotein and viral RNA-dependent RNA polymerases (RdRp), PB1, PB2, and PA subunits. The vRNP complex catalyzes both genome replication and transcription reactions. PB1 contains the motifs highly conserved among RdRps...

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Detalles Bibliográficos
Autores principales: Binh, Nguyen Trong, Wakai, Chitose, Kawaguchi, Atsushi, Nagata, Kyosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866587/
https://www.ncbi.nlm.nih.gov/pubmed/24391632
http://dx.doi.org/10.3389/fmicb.2013.00398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866587/
https://www.ncbi.nlm.nih.gov/pubmed/24391632
http://dx.doi.org/10.3389/fmicb.2013.00398

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