XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway

BACKGROUND: Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. The present treatment including surgery, chemotherapy and radiation, which have only 40% long-term cure rates, and usually cause tumor recurrence. Thus, looking for new effective and less toxic therapies has imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Xiao-Hong, Hou, Wei-Jian, Fang, Yan, Fan, Jun, Tong, Hao, Bai, Shu-Ling, Chen, Qu, Xu, He, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866601/
https://www.ncbi.nlm.nih.gov/pubmed/24308762
http://dx.doi.org/10.1186/1756-9966-32-100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866601/
https://www.ncbi.nlm.nih.gov/pubmed/24308762
http://dx.doi.org/10.1186/1756-9966-32-100

Ejemplares similares