The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice

BACKGROUND: Both L-4F, one apolipoprotein A-1 mimetic peptide, and statins can reduce progression of atherosclerosis by different mechanisms. The combination of the two drugs can cause lesion regression by rendering HDL anti-inflammatory. We postulated that combination of L-4F and simvastatin may st...

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Detalles Bibliográficos
Autores principales: Ying, Ru, Yuan, Yong, Qin, Ya-Fei, Tian, Di, Feng, Li, Guo, Zhi-Gang, Sun, Yan-Xiang, Li, Ming-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866605/
https://www.ncbi.nlm.nih.gov/pubmed/24314261
http://dx.doi.org/10.1186/1476-511X-12-180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866605/
https://www.ncbi.nlm.nih.gov/pubmed/24314261
http://dx.doi.org/10.1186/1476-511X-12-180

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