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Exploring the “dark matter” of a mammalian proteome by protein structure and function modeling

BACKGROUND: A growing body of evidence shows that gene products encoded by short open reading frames play key roles in numerous cellular processes. Yet, they are generally overlooked in genome assembly, escaping annotation because small protein-coding genes are difficult to predict computationally....

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Detalles Bibliográficos
Autor principal: Brylinski, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866606/
https://www.ncbi.nlm.nih.gov/pubmed/24321360
http://dx.doi.org/10.1186/1477-5956-11-47