Design, Synthesis and Biological Evaluation of N4-Sulfonamido-Succinamic, Phthalamic, Acrylic and Benzoyl Acetic Acid Derivatives as Potential DPP IV Inhibitors

As incidence rate of type II diabetes mellitus continues to rise, there is a growing need to identify novel therapeutic agents with improved efficacy and reduced side effects. Dipeptidyl peptidase IV (DPP IV) is a multifunctional protein involved in many physiological processes. It deactivates the n...

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Detalles Bibliográficos
Autores principales: Khalaf, Reema Abu, Sheikha, Ghassan Abu, Al-Sha'er, Mahmoud, Taha, Mutasem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866624/
https://www.ncbi.nlm.nih.gov/pubmed/24358058
http://dx.doi.org/10.2174/1874104501307010039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866624/
https://www.ncbi.nlm.nih.gov/pubmed/24358058
http://dx.doi.org/10.2174/1874104501307010039

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