Cargando…

Stable assembly of HIV-1 export complexes occurs cotranscriptionally

The HIV-1 Rev protein mediates export of unspliced and singly spliced viral transcripts by binding to the Rev response element (RRE) and recruiting the cellular export factor CRM1. Here, we investigated the recruitment of Rev to the transcription sites of HIV-1 reporters that splice either post- or...

Descripción completa

Detalles Bibliográficos
Autores principales: Nawroth, Isabel, Mueller, Florian, Basyuk, Eugenia, Beerens, Nancy, Rahbek, Ulrik L., Darzacq, Xavier, Bertrand, Edouard, Kjems, Jørgen, Schmidt, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866638/
https://www.ncbi.nlm.nih.gov/pubmed/24255166
http://dx.doi.org/10.1261/rna.038182.113