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Studies of translational misreading in vivo show that the ribosome very efficiently discriminates against most potential errors
Protein synthesis must rapidly and repeatedly discriminate between a single correct and many incorrect aminoacyl-tRNAs. We have attempted to measure the frequencies of all possible missense errors by tRNA[Image: see text], tRNA[Image: see text] and tRNA[Image: see text]. The most frequent errors inv...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866648/ https://www.ncbi.nlm.nih.gov/pubmed/24249223 http://dx.doi.org/10.1261/rna.039792.113 |