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High and low frequency stimulation of the subthalamic nucleus induce prolonged changes in subthalamic and globus pallidus neurons

High frequency stimulation (HFS) of the subthalamic nucleus (STN) is widely used to treat the symptoms of Parkinson’s disease (PD) but the mechanism of this therapy is unclear. Using a rat brain slice preparation maintaining the connectivity between the STN and one of its target nuclei, the globus p...

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Detalles Bibliográficos
Autores principales: Lavian, Hagar, Ben-Porat, Hana, Korngreen, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866651/
https://www.ncbi.nlm.nih.gov/pubmed/24391553
http://dx.doi.org/10.3389/fnsys.2013.00073