Pharmacokinetic Delivery and Metabolizing Rate of Nicardipine Incorporated in Hydrophilic and Hydrophobic Cyclodextrins Using Two-Compartment Mathematical Model

The dispersion routes of cyclodextrin complexes with nicardipine (NC), such as hydrophilic hydroxypropyl-β-cyclodextrin (NC/HPβCD) and hydrophobic triacetyl-β-cyclodextrin (NC/TAβCD), through the body for controlled drug delivery and sustained release have been examined. The two-compartment pharmaco...

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Detalles Bibliográficos
Autores principales: Shityakov, Sergey, Förster, Carola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866780/
https://www.ncbi.nlm.nih.gov/pubmed/24391458
http://dx.doi.org/10.1155/2013/131358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866780/
https://www.ncbi.nlm.nih.gov/pubmed/24391458
http://dx.doi.org/10.1155/2013/131358

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