Correlating efficacy and desensitization with GluK2 ligand-binding domain movements

Gating of AMPA- and kainate-selective ionotropic glutamate receptors can be defined in terms of ligand affinity, efficacy and the rate and extent of desensitization. Crucial insights into all three elements have come from structural studies of the ligand-binding domain (LBD). In particular, binding-...

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Detalles Bibliográficos
Autores principales: Nayeem, Naushaba, Mayans, Olga, Green, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866869/
https://www.ncbi.nlm.nih.gov/pubmed/23720540
http://dx.doi.org/10.1098/rsob.130051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866869/
https://www.ncbi.nlm.nih.gov/pubmed/23720540
http://dx.doi.org/10.1098/rsob.130051

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