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An aryl hydrocarbon receptor induces VEGF expression through ATF4 under glucose deprivation in HepG2

BACKGROUND: Aryl hydrocarbon receptor (AhR) not only regulates drug-metabolizing enzyme expression but also regulates cancer malignancy. The steps to the development of malignancy include angiogenesis that is induced by tumor microenvironments, hypoxia, and nutrient deprivation. Vascular endothelial...

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Detalles Bibliográficos
Autores principales: Terashima, Jun, Tachikawa, Chie, Kudo, Kenzo, Habano, Wataru, Ozawa, Shogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866938/
https://www.ncbi.nlm.nih.gov/pubmed/24330582
http://dx.doi.org/10.1186/1471-2199-14-27