The Metalloprotease ADAM12 Regulates the Effector Function of Human Th17 Cells

A key modulator of immune homeostasis, TGFβ has an important role in the differentiation of regulatory T cells (Tregs) and IL-17-secreting T cells (Th17). How TGFβ regulates these functionally opposing T cell subsets is not well understood. We determined that an ADAM family metalloprotease called AD...

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Detalles Bibliográficos
Autores principales: Zhou, Angela X., El Hed, Aimee, Mercer, Frances, Kozhaya, Lina, Unutmaz, Derya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867213/
https://www.ncbi.nlm.nih.gov/pubmed/24363794
http://dx.doi.org/10.1371/journal.pone.0081146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867213/
https://www.ncbi.nlm.nih.gov/pubmed/24363794
http://dx.doi.org/10.1371/journal.pone.0081146

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