NanoDisk containing super aggregated amphotericin B: a high therapeutic index antifungal formulation with enhanced potency

OBJECTIVES: NanoDisk–amphotericin B (ND-AMB) is a protein-phospholipid bioparticle containing a “super aggregate” form of antifungal AMB. While lipid-based formulations of AMB, including liposomal AMB (L-AMB), are safer than the deoxycholate (DOC) solubilized form (DOC-AMB), the potency of lipid-bas...

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Detalles Bibliográficos
Autores principales: Burgess, Braydon L, He, Yumin, Baker, Mandie M, Luo, Bing, Carroll, Stephen F, Forte, Trudy M, Oda, Michael N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867322/
https://www.ncbi.nlm.nih.gov/pubmed/24379661
http://dx.doi.org/10.2147/IJN.S50113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867322/
https://www.ncbi.nlm.nih.gov/pubmed/24379661
http://dx.doi.org/10.2147/IJN.S50113

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