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NanoDisk containing super aggregated amphotericin B: a high therapeutic index antifungal formulation with enhanced potency

OBJECTIVES: NanoDisk–amphotericin B (ND-AMB) is a protein-phospholipid bioparticle containing a “super aggregate” form of antifungal AMB. While lipid-based formulations of AMB, including liposomal AMB (L-AMB), are safer than the deoxycholate (DOC) solubilized form (DOC-AMB), the potency of lipid-bas...

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Detalles Bibliográficos
Autores principales:	Burgess, Braydon L, He, Yumin, Baker, Mandie M, Luo, Bing, Carroll, Stephen F, Forte, Trudy M, Oda, Michael N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867322/ https://www.ncbi.nlm.nih.gov/pubmed/24379661 http://dx.doi.org/10.2147/IJN.S50113

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