Conformation and Stability of Intramolecular Telomeric G-Quadruplexes: Sequence Effects in the Loops

Telomeres are guanine-rich sequences that protect the ends of chromosomes. These regions can fold into G-quadruplex structures and their stabilization by G-quadruplex ligands has been employed as an anticancer strategy. Genetic analysis in human telomeres revealed extensive allelic variation restric...

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Detalles Bibliográficos
Autores principales: Sattin, Giovanna, Artese, Anna, Nadai, Matteo, Costa, Giosuè, Parrotta, Lucia, Alcaro, Stefano, Palumbo, Manlio, Richter, Sara N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867476/
https://www.ncbi.nlm.nih.gov/pubmed/24367632
http://dx.doi.org/10.1371/journal.pone.0084113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867476/
https://www.ncbi.nlm.nih.gov/pubmed/24367632
http://dx.doi.org/10.1371/journal.pone.0084113

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