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Transcriptional Regulation of the HMGA1 Gene by Octamer-Binding Proteins Oct-1 and Oct-2
The High-Mobility Group AT-Hook 1 (HMGA1) protein is an architectural transcription factor that binds to AT-rich sequences in the promoter region of DNA and functions as a specific cofactor for gene activation. Previously, we demonstrated that HMGA1 is a key regulator of the insulin receptor (INSR)...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867479/ https://www.ncbi.nlm.nih.gov/pubmed/24367622 http://dx.doi.org/10.1371/journal.pone.0083969 |