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No Association between Loss-of-Function Mutations in filaggrin and Diabetes, Cardiovascular Disease, and All-Cause Mortality

BACKGROUND: Common loss-of-function mutations in the filaggrin gene (FLG) are a major predisposing risk factor for atopic disease due to reduced epidermal filaggrin protein levels. We previously observed an association between these mutations and type 2 diabetes and hypothesized that an inherited im...

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Detalles Bibliográficos
Autores principales: Husemoen, Lise Lotte N., Skaaby, Tea, Jørgensen, Torben, Thyssen, Jacob P., Meldgaard, Michael, Szecsi, Pal B., Stender, Steen, Johansen, Jeanne Duus, Linneberg, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867483/
https://www.ncbi.nlm.nih.gov/pubmed/24367652
http://dx.doi.org/10.1371/journal.pone.0084293