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Activity in prelimbic cortex subserves fear memory reconsolidation over time

The prelimbic cortex has been implicated in the consolidation of previously learned fear. Herein, we report that temporarily inactivating this medial prefrontal cortex subregion with the GABA(A) agonist muscimol (4.0 nmol in 0.2 μL per hemisphere) was able to equally disrupt 1-, 7-, and 21-d-old con...

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Detalles Bibliográficos
Autores principales: Stern, Cristina A.J., Gazarini, Lucas, Vanvossen, Ana C., Hames, Mayara S., Bertoglio, Leandro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867715/
https://www.ncbi.nlm.nih.gov/pubmed/24344180
http://dx.doi.org/10.1101/lm.032631.113