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Melatonin Improves Outcomes of Heatstroke in Mice by Reducing Brain Inflammation and Oxidative Damage and Multiple Organ Dysfunction

We report here that when untreated mice underwent heat stress, they displayed thermoregulatory deficit (e.g., animals display hypothermia during room temperature exposure), brain (or hypothalamic) inflammation, ischemia, oxidative damage, hypothalamic-pituitary-adrenal axis impairment (e.g., decreas...

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Detalles Bibliográficos
Autores principales: Tian, Yu-Feng, Lin, Cheng-Hsien, Hsu, Shu-Fen, Lin, Mao-Tsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867919/
https://www.ncbi.nlm.nih.gov/pubmed/24369441
http://dx.doi.org/10.1155/2013/349280