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Efficient computation of minimal perturbation sets in gene regulatory networks

In the last few decades, technological and experimental advancements have enabled a more precise understanding of the mode of action of drugs with respect to human cell signaling pathways and have positively influenced the design of new drug compounds. However, as the design of compounds has become...

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Detalles Bibliográficos
Autores principales: Garg, Abhishek, Mohanram, Kartik, Di Cara, Alessandro, Degueurce, Gwendoline, Ibberson, Mark, Dorier, Julien, Xenarios, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867968/
https://www.ncbi.nlm.nih.gov/pubmed/24391592
http://dx.doi.org/10.3389/fphys.2013.00361