Hepatocyte Growth Factor/c-Met Signaling Is Required for β-Cell Regeneration

Hepatocyte growth factor (HGF) is a mitogen required for β-cell replication during pregnancy. To determine whether HGF/c-Met signaling is required for β-cell regeneration, we characterized mice with pancreatic deletion of the HGF receptor, c-Met (PancMet KO mice), in two models of reduced β-cell mas...

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Detalles Bibliográficos
Autores principales: Alvarez-Perez, Juan Carlos, Ernst, Sara, Demirci, Cem, Casinelli, Gabriella P., Mellado-Gil, Jose Manuel D., Rausell-Palamos, Francisco, Vasavada, Rupangi C., Garcia-Ocaña, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868042/
https://www.ncbi.nlm.nih.gov/pubmed/24089510
http://dx.doi.org/10.2337/db13-0333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868042/
https://www.ncbi.nlm.nih.gov/pubmed/24089510
http://dx.doi.org/10.2337/db13-0333

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