Multiple HLA Epitopes Contribute to Type 1 Diabetes Susceptibility

Disease susceptibility for type 1 diabetes is strongly associated with the inheritance of specific HLA alleles. However, conventional allele frequency analysis can miss HLA associations because many alleles are rare. In addition, disparate alleles that have similar peptide-binding sites, or shared e...

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Detalles Bibliográficos
Autores principales: Roark, Christina L., Anderson, Kirsten M., Simon, Lucas J., Schuyler, Ronald P., Aubrey, Michael T., Freed, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868045/
https://www.ncbi.nlm.nih.gov/pubmed/24357703
http://dx.doi.org/10.2337/db13-1153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868045/
https://www.ncbi.nlm.nih.gov/pubmed/24357703
http://dx.doi.org/10.2337/db13-1153

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