Protective CD8(+) T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

Induction of antigen-specific CD8(+) T cells offers the prospect of immunization against many infectious diseases, but no subunit vaccine has induced CD8(+) T cells that correlate with efficacy in humans. Here we demonstrate that a replication-deficient chimpanzee adenovirus vector followed by a mod...

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Detalles Bibliográficos
Autores principales: Ewer, Katie J., O’Hara, Geraldine A., Duncan, Christopher J. A., Collins, Katharine A., Sheehy, Susanne H., Reyes-Sandoval, Arturo, Goodman, Anna L., Edwards, Nick J., Elias, Sean C., Halstead, Fenella D., Longley, Rhea J., Rowland, Rosalind, Poulton, Ian D., Draper, Simon J., Blagborough, Andrew M., Berrie, Eleanor, Moyle, Sarah, Williams, Nicola, Siani, Loredana, Folgori, Antonella, Colloca, Stefano, Sinden, Robert E., Lawrie, Alison M., Cortese, Riccardo, Gilbert, Sarah C., Nicosia, Alfredo, Hill, Adrian V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868203/
https://www.ncbi.nlm.nih.gov/pubmed/24284865
http://dx.doi.org/10.1038/ncomms3836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868203/
https://www.ncbi.nlm.nih.gov/pubmed/24284865
http://dx.doi.org/10.1038/ncomms3836

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