Harnessing of the Nucleosome Remodeling Deacetylase complex controls lymphocyte development and prevents leukemogenesis

Cell fate decisions depend on the interplay between chromatin regulators and transcription factors. Here we show that activity of the Mi-2β nucleosome remodeling and deacetylase (NuRD) complex was controlled by the Ikaros family of lymphoid-lineage determining proteins. Ikaros, an integral component...

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Detalles Bibliográficos
Autores principales: Zhang, Jiangwen, Jackson, Audrey F., Naito, Taku, Dose, Marei, Seavitt, John, Liu, Feifei, Heller, Elizabeth J., Kashiwagi, Mariko, Yoshida, Toshimi, Gounari, Fotini, Petrie, Howard T., Georgopoulos, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868219/
https://www.ncbi.nlm.nih.gov/pubmed/22080921
http://dx.doi.org/10.1038/ni.2150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868219/
https://www.ncbi.nlm.nih.gov/pubmed/22080921
http://dx.doi.org/10.1038/ni.2150

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