K-Map: connecting kinases with therapeutics for drug repurposing and development

Protein kinases play important roles in regulating signal transduction in eukaryotic cells. Due to evolutionary conserved binding sites in the catalytic domain of the kinases, most inhibitors that target these sites promiscuously inhibit multiple kinases. Quantitative analysis can reveal complex and...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jihye, Yoo, Minjae, Kang, Jaewoo, Tan, Aik Choon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Genome Database
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868238/
https://www.ncbi.nlm.nih.gov/pubmed/24060470
http://dx.doi.org/10.1186/1479-7364-7-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868238/
https://www.ncbi.nlm.nih.gov/pubmed/24060470
http://dx.doi.org/10.1186/1479-7364-7-20

Ejemplares similares