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LINEs of evidence: noncanonical DNA replication as an epigenetic determinant
LINE-1 (L1) retrotransposons are repetitive elements in mammalian genomes. They are capable of synthesizing DNA on their own RNA templates by harnessing reverse transcriptase (RT) that they encode. Abundantly expressed full-length L1s and their RT are found to globally influence gene expression prof...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868326/ https://www.ncbi.nlm.nih.gov/pubmed/24034780 http://dx.doi.org/10.1186/1745-6150-8-22 |