Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis

Background and objectives: Multidrug resistant (MDR) bacteria are a growing threat to global health. Studies focusing on single antibiotics have shown that drug resistance is often associated with a fitness cost in the absence of drug. However, little is known about the fitness cost associated with...

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Detalles Bibliográficos
Autores principales: Borrell, Sònia, Teo, Youjin, Giardina, Federica, Streicher, Elizabeth M., Klopper, Marisa, Feldmann, Julia, Müller, Borna, Victor, Tommie C., Gagneux, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868377/
https://www.ncbi.nlm.nih.gov/pubmed/24481187
http://dx.doi.org/10.1093/emph/eot003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868377/
https://www.ncbi.nlm.nih.gov/pubmed/24481187
http://dx.doi.org/10.1093/emph/eot003

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