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Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis
Background and objectives: Multidrug resistant (MDR) bacteria are a growing threat to global health. Studies focusing on single antibiotics have shown that drug resistance is often associated with a fitness cost in the absence of drug. However, little is known about the fitness cost associated with...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868377/ https://www.ncbi.nlm.nih.gov/pubmed/24481187 http://dx.doi.org/10.1093/emph/eot003 |