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Windfalls and pitfalls: Applications of population genetics to the search for disease genes

Association mapping can be viewed as an application of population genetics and evolutionary biology to the problem of identifying genes causally connected to phenotypes. However, some population-genetic principles important to the design and analysis of association studies have not been widely under...

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Detalles Bibliográficos
Autores principales: Edge, Michael D., Gorroochurn, Prakash, Rosenberg, Noah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868415/
https://www.ncbi.nlm.nih.gov/pubmed/24481204
http://dx.doi.org/10.1093/emph/eot021