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Windfalls and pitfalls: Applications of population genetics to the search for disease genes
Association mapping can be viewed as an application of population genetics and evolutionary biology to the problem of identifying genes causally connected to phenotypes. However, some population-genetic principles important to the design and analysis of association studies have not been widely under...
Autores principales: | Edge, Michael D., Gorroochurn, Prakash, Rosenberg, Noah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868415/ https://www.ncbi.nlm.nih.gov/pubmed/24481204 http://dx.doi.org/10.1093/emph/eot021 |
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