Essential regulation of cell bioenergetics in Trypanosoma brucei by the mitochondrial calcium uniporter

Mechanisms of regulation of mitochondrial metabolism in trypanosomes are not completely understood. Here we present evidence that the Trypanosoma brucei mitochondrial calcium uniporter (TbMCU) is essential for regulation of mitochondrial bioenergetics, autophagy, and cell death, even in the bloodstr...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Guozhong, Vercesi, Anibal E., Docampo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868461/
https://www.ncbi.nlm.nih.gov/pubmed/24305511
http://dx.doi.org/10.1038/ncomms3865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868461/
https://www.ncbi.nlm.nih.gov/pubmed/24305511
http://dx.doi.org/10.1038/ncomms3865

Ejemplares similares