Cargando…

Inactivation of Metabolic Genes Causes Short- and Long-Range dys-Regulation in Escherichia coli Metabolic Network

The metabolic network in E. coli can be severely affected by the inactivation of metabolic genes that are required to catabolize a nutrient (D-galactose). We hypothesized that the resulting accumulation of small molecules can yield local as well as systemic effects on the metabolic network. Analysis...

Descripción completa

Detalles Bibliográficos
Autores principales: Barupal, Dinesh Kumar, Lee, Sang Jun, Karoly, Edward D., Adhya, Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868466/
https://www.ncbi.nlm.nih.gov/pubmed/24363806
http://dx.doi.org/10.1371/journal.pone.0078360