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Destabilization of MYC/MYCN by the mitochondrial inhibitors, metaiodobenzylguanidine, metformin and phenformin

In the present study, we investigated the anticancer effects of the mitochondrial inhibitors, metaiodobenzylguanidine (MIBG), metformin and phenformin. (131)I-MIBG has been used for scintigraphic detection and the targeted radiotherapy of neuroblastoma (NB), a pediatric malignancy. Non-radiolabeled...

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Detalles Bibliográficos
Autores principales: WANG, STEPHANIE S., HSIAO, RUTH, LIMPAR, MARIKO M., LOMAHAN, SARAH, TRAN, TUAN-ANH, MALONEY, NOLAN J., IKEGAKI, NAOHIKO, TANG, XAO X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868499/
https://www.ncbi.nlm.nih.gov/pubmed/24190252
http://dx.doi.org/10.3892/ijmm.2013.1545