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αvβ6- and αvβ8-Integrins Serve As Interchangeable Receptors for HSV gH/gL to Promote Endocytosis and Activation of Membrane Fusion

Herpes simplex virus (HSV) - and herpesviruses in general - encode for a multipartite entry/fusion apparatus. In HSV it consists of the HSV-specific glycoprotein D (gD), and three additional glycoproteins, gH/gL and gB, conserved across the Herpesviridae family and responsible for the execution of f...

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Detalles Bibliográficos
Autores principales: Gianni, Tatiana, Salvioli, Stefano, Chesnokova, Liudmila S., Hutt-Fletcher, Lindsey M., Campadelli-Fiume, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868510/
https://www.ncbi.nlm.nih.gov/pubmed/24367260
http://dx.doi.org/10.1371/journal.ppat.1003806