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Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

Tuberculosis is a current major world-health problem, exacerbated by the causative pathogen, Mycobacterium tuberculosis (Mtb), becoming increasingly resistant to conventional antibiotic treatment. Mtb is able to counteract the bactericidal mechanisms of leukocytes to survive intracellularly and deve...

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Detalles Bibliográficos
Autores principales: Elks, Philip M., Brizee, Sabrina, van der Vaart, Michiel, Walmsley, Sarah R., van Eeden, Fredericus J., Renshaw, Stephen A., Meijer, Annemarie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868520/
https://www.ncbi.nlm.nih.gov/pubmed/24367256
http://dx.doi.org/10.1371/journal.ppat.1003789