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Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism
Tuberculosis is a current major world-health problem, exacerbated by the causative pathogen, Mycobacterium tuberculosis (Mtb), becoming increasingly resistant to conventional antibiotic treatment. Mtb is able to counteract the bactericidal mechanisms of leukocytes to survive intracellularly and deve...
Autores principales: | Elks, Philip M., Brizee, Sabrina, van der Vaart, Michiel, Walmsley, Sarah R., van Eeden, Fredericus J., Renshaw, Stephen A., Meijer, Annemarie H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868520/ https://www.ncbi.nlm.nih.gov/pubmed/24367256 http://dx.doi.org/10.1371/journal.ppat.1003789 |
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