The Stress-Regulated Transcription Factor CHOP Promotes Hepatic Inflammatory Gene Expression, Fibrosis, and Oncogenesis

Viral hepatitis, obesity, and alcoholism all represent major risk factors for hepatocellular carcinoma (HCC). Although these conditions also lead to integrated stress response (ISR) or unfolded protein response (UPR) activation, the extent to which these stress pathways influence the pathogenesis of...

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Detalles Bibliográficos
Autores principales: DeZwaan-McCabe, Diane, Riordan, Jesse D., Arensdorf, Angela M., Icardi, Michael S., Dupuy, Adam J., Rutkowski, D. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868529/
https://www.ncbi.nlm.nih.gov/pubmed/24367269
http://dx.doi.org/10.1371/journal.pgen.1003937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868529/
https://www.ncbi.nlm.nih.gov/pubmed/24367269
http://dx.doi.org/10.1371/journal.pgen.1003937

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