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Genome-Wide RNAi Screen Identifies Novel Host Proteins Required for Alphavirus Entry

The enveloped alphaviruses include important and emerging human pathogens such as Chikungunya virus and Eastern equine encephalitis virus. Alphaviruses enter cells by clathrin-mediated endocytosis, and exit by budding from the plasma membrane. While there has been considerable progress in defining t...

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Detalles Bibliográficos
Autores principales: Ooi, Yaw Shin, Stiles, Katie M., Liu, Catherine Y., Taylor, Gwen M., Kielian, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868536/
https://www.ncbi.nlm.nih.gov/pubmed/24367265
http://dx.doi.org/10.1371/journal.ppat.1003835