Transcription Factor Occupancy Can Mediate Active Turnover of DNA Methylation at Regulatory Regions

Distal regulatory elements, including enhancers, play a critical role in regulating gene activity. Transcription factor binding to these elements correlates with Low Methylated Regions (LMRs) in a process that is poorly understood. Here we ask whether and how actual occupancy of DNA-binding factors...

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Detalles Bibliográficos
Autores principales: Feldmann, Angelika, Ivanek, Robert, Murr, Rabih, Gaidatzis, Dimos, Burger, Lukas, Schübeler, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868540/
https://www.ncbi.nlm.nih.gov/pubmed/24367273
http://dx.doi.org/10.1371/journal.pgen.1003994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868540/
https://www.ncbi.nlm.nih.gov/pubmed/24367273
http://dx.doi.org/10.1371/journal.pgen.1003994

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