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Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia

RNA-seq is a promising technology to re-sequence protein coding genes for the identification of single nucleotide variants (SNV), while simultaneously obtaining information on structural variations and gene expression perturbations. We asked whether RNA-seq is suitable for the detection of driver mu...

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Detalles Bibliográficos
Autores principales: Kalender Atak, Zeynep, Gianfelici, Valentina, Hulselmans, Gert, De Keersmaecker, Kim, Devasia, Arun George, Geerdens, Ellen, Mentens, Nicole, Chiaretti, Sabina, Durinck, Kaat, Uyttebroeck, Anne, Vandenberghe, Peter, Wlodarska, Iwona, Cloos, Jacqueline, Foà, Robin, Speleman, Frank, Cools, Jan, Aerts, Stein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868543/
https://www.ncbi.nlm.nih.gov/pubmed/24367274
http://dx.doi.org/10.1371/journal.pgen.1003997