EPS8 Inhibition Increases Cisplatin Sensitivity in Lung Cancer Cells

Cisplatin, a commonly used chemotherapeutic, is associated with ototoxicity, renal toxicity and neurotoxicity, thus identifying means to increase the therapeutic index of cisplatin may allow for improved outcomes. A SNP (rs4343077) within EPS8, discovered through a genome wide association study of c...

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Detalles Bibliográficos
Autores principales: Gorsic, Lidija K., Stark, Amy L., Wheeler, Heather E., Wong, Shan S., Im, Hae K., Dolan, M. Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868552/
https://www.ncbi.nlm.nih.gov/pubmed/24367505
http://dx.doi.org/10.1371/journal.pone.0082220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868552/
https://www.ncbi.nlm.nih.gov/pubmed/24367505
http://dx.doi.org/10.1371/journal.pone.0082220

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